The National Ataxia Foundation (NAF) Board of Directors and staff announced their new Executive Director, Andrew Rosen, following a nationwide search conducted by a committee of the Board of Directors. He will lead NAF’s efforts in improving the lives of persons affected by Ataxia through support, education, and research.
Non-profit based in Minneapolis will accept resumes from qualified candidates until the position is filled, with submissions to be considered in the first screening due by December 21, 2018. Download Press Release
Using biochemical and structural studies, they found that in AOA1, aprataxin mutations affect protein stability, how repair proteins bind to DNA, and the rate of the chemical reaction, which is known as catalysis. The team also uncovered a dominant mutation that affects the enzymatic reaction that normally reverses DNA damage. Read more »